Succinic acid production method
There are many industrial manufacturing methods, mainly as follows:
1. Oxidation method, paraffin wax is deeply oxidized to generate a mixture of various carboxylic acids, and then succinic acid can be obtained after separation steps such as steam distillation and crystallization.
2. Hydrogenation method, maleic anhydride or fumaric acid is hydrogenated under the action of a catalyst to generate succinic acid, which is then separated to obtain the finished product. The catalyst is nickel or noble metal, and the reaction temperature is about 130-140°C.
3. Acrylic acid carbonyl synthesis method, acrylic acid and carbon monoxide will generate succinic acid under the action of a catalyst. Not yet industrialized.
4. Electrolytic oxidation method, phthalic anhydride, sulfuric acid and water are electrolyzed in a ceramic electrolytic cell at a ratio of 1:0.5:4 to obtain succinic acid. The raw material for electrolysis synthesis is maleic acid or maleic anhydride, the anion and anolyte are dilute sulfuric acid, separated by a cation membrane, the anode and the anode are generally made of lead plates, usually synthesized in a plate-and-frame electrolytic cell.
5. Acetylene method, acetylene reacts with carbon monoxide and water in the presence of [Co(CO)4] catalyst in an acidic medium to obtain succinic acid. The reaction temperature is 80-250°C and the pressure is 2.94-49.03MPa.
6. Emerging fermentation method. Compared with traditional chemical methods, the production of succinic acid by microbial fermentation has many advantages: the production cost is competitive; the use of renewable agricultural resources including carbon dioxide as raw materials avoids dependence on petrochemical raw materials; and reduces the environmental impact of chemical synthesis processes. Pollution.