Five production methods of o-chlorobenzoic acid

1. O-chlorotoluene is used as raw material for chlorination under photocatalysis to generate trichloromethyl o-chlorobenzene, which is then obtained by hydrolysis.

2. It is obtained by oxidation with o-chlorotoluene as raw material and potassium permanganate as oxidant.

3. Using anthranilic acid as raw material, diazotizing reaction with sodium nitrite in hydrochloric acid solution to generate diazonium salt, which is obtained by reacting with hydrochloric acid under the action of copper chloride.

4. Chlorinated hydrolysis of o-chlorotoluene

Place the o-chlorotoluene in the reaction kettle, illuminate it with ultraviolet light, the reaction temperature is 100℃, and pass chlorine gas to carry out the chlorination reaction, deepen the depth of the chlorination reaction to produce α, α, α, 2-tetrachlorotoluene, or use o-chlorine Toluene is the raw material, and azobisisobutyronitrile is used as the catalyst for chlorination, and α,α,α,2-tetrachlorotoluene can also be obtained, and then the above product is transferred to the hydrolysis kettle, and a little acid is added to hydrolyze to form o-chlorobenzene For formyl chloride, 2-chlorobenzoic acid can be obtained if the hydrolysis depth is large.

5. Anthranilic acid diazotization method

Add hydrochloric acid and sodium nitrite as raw materials to diazotize anthranilic acid, then add a solution of Cu2Cl2 dissolved in hydrochloric acid to the diazonium solution, stir while adding, and obtain o-chlorobenzoic acid after post-treatment