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The main uses of 8-hydroxyquinoline

TIME:22-10-28    NUM:0

1.Used as a pharmaceutical intermediate, it is the raw material for synthesizing Kexielining, Clioquinoline, and Promethazine, as well as an intermediate for dyes and pesticides. This product is an intermediate of halogenated quinoline anti-amebic drugs, including quiniodoform, chloroiodoquinoline, diiodoquinoline, etc. These drugs exert anti-amebic effects by inhibiting intestinal commensal bacteria, and are effective against amoebic dysentery, but have no effect on extra-intestinal amoebic parasites. It has been reported abroad that this class of drugs can cause subacute spinal optic neuropathy, so this drug has been banned in Japan and the United States. Diiodoquine is less common than clioquinoline to cause this disease. 8-Hydroxyquinoline is also an intermediate for dyes and pesticides. Its sulfate and copper salts are excellent preservatives, disinfectants and mold inhibitors. This product is a complexometric titration indicator for chemical analysis.

 

2. Used as complexing agent and extraction agent for precipitation and separation of metal ions. Standard for the Determination of Heterocyclic Nitrogen by Organic Microanalysis, Organic Synthesis. It is also an intermediate for dyes, pesticides and halogenated quinoline anti-amebic drugs. Its sulfate and copper salts are excellent preservatives.

 

3. Adding epoxy resin adhesive can improve the bonding strength and heat aging resistance to metals (especially stainless steel), and the dosage is generally 0.5 to 3 parts. It is an intermediate of halogenated quinoline anti-amebic drugs, as well as an intermediate of pesticides and dyes. It can be used as antifungal agent, industrial preservative and stabilizer of polyester resin, phenolic resin and hydrogen peroxide, and it is also a complexometric titration indicator for chemical analysis.

 

4. This product is an intermediate of halogenated quinoline drugs, as well as an intermediate of dyes and pesticides. Its sulfate and copper salts are excellent preservatives, disinfectants and mold inhibitors. The maximum allowable content (mass fraction) in cosmetics is 0.3%. Sunscreen products and products for children under 3 years old (such as talcum powder) are prohibited, and the product label should indicate "Forbidden for children under 3 years old". When dealing with bacterial-infected skin and bacterial-infected eczema, the mass fraction of 8-hydroxyquinoline in the emulsion is 0.001% to 0.02%. It is also used as a disinfectant, antiseptic and bactericide, and its anti-mold effect is strong. The content (mass fraction) of 8-hydroxyquinoline potassium sulfate used in skin creams and lotions is 0.05% to 0.5%